You mean OrbitControls.setCameraAndLookTarget ?
This looks correct: Needle-engine - Vite Template (forked) - StackBlitz
Do you think you could share more info how your setup is / how you call that method - maybe provide a reproducible example
Edit: It reproduces in Unity when the object has a camera - will look into it
Edit2: Ok the regression is caused by a change where the look direction should be in Z. However cameras in three.js look into -Z. This regression will be fixed in 4.4.3